Adco Contromet Tablet is a medication that belongs to the class of gastrointestinal antispasmodics and cholinolytics. It is used for various purposes, such as:
- As an adjunct to X-ray examinations of the gastrointestinal tract
- To treat post-operative hypotonia (postvagotomy syndrome)
- To prevent and treat nausea and vomiting caused by radiation sickness or surgery
Adco Contromet Tablet has some contraindications, warnings, and precautions that should be considered before using it. It may also cause some side effects, such as tardive dyskinesia, extrapyramidal symptoms, bowel upsets, drowsiness, fatigue, dizziness, restlessness, anxiety, galactorrhea, gynecomastia, transient increases in plasma aldosterone concentrations, and hypertensive crises.
Adco Contromet Tablet should be taken as prescribed by the doctor, following the dosage and administration instructions. In case of an overdose, immediate medical attention is required.
Adco Contromet Tablet is manufactured by Adcock Ingram Limited, a leading pharmaceutical company in South Africa. It is available in tablet and syrup forms, and can be purchased with a prescription from a pharmacy.
Introduction
Adco Contromet Tablet is a medication that contains metoclopramide hydrochloride as the active ingredient. Metoclopramide hydrochloride is a derivative of benzamide, and it acts as a dopamine antagonist and a cholinergic stimulant. It has both central and peripheral effects on the gastrointestinal tract, as well as anti-emetic properties.
Adco Contromet Tablet is classified as a gastrointestinal antispasmodic and a cholinolytic. It is used for various purposes, such as:
- As an adjunct to X-ray examinations of the gastrointestinal tract
- To treat post-operative hypotonia (postvagotomy syndrome)
- To prevent and treat nausea and vomiting caused by radiation sickness or surgery
In this blog post, we will discuss what Adco Contromet Tablet is, how it works, what it is used for, what are the contraindications, warnings, and precautions, what are the dosage and administration instructions, what are the side effects, what to do in case of an overdose, and what are the presentation and manufacturer details. We will also answer some frequently asked questions about Adco Contromet Tablet.
What is Adco Contromet Tablet?
Adco Contromet Tablet is a medication that contains metoclopramide hydrochloride as the active ingredient. Metoclopramide hydrochloride is a derivative of benzamide, and it acts as a dopamine antagonist and a cholinergic stimulant. It has both central and peripheral effects on the gastrointestinal tract, as well as anti-emetic properties.
Metoclopramide hydrochloride works by:
- Increasing the tone and amplitude of gastric contractions, especially in the antrum and duodenum
- Relaxing the pyloric sphincter and the duodenal bulb
- Increasing the peristaltic activity of the duodenum and jejunum
- Enhancing the gastric emptying and intestinal transit of liquids and solids
- Increasing the lower esophageal sphincter pressure and preventing gastroesophageal reflux
- Stimulating the chemoreceptor trigger zone in the medulla oblongata and blocking the dopamine receptors in the vomiting center
- Inhibiting the central and peripheral effects of apomorphine, a dopamine agonist
- Increasing the release of acetylcholine from the myenteric plexus
- Potentiating the action of neostigmine, a cholinesterase inhibitor
Adco Contromet Tablet is available in tablet and syrup forms, and can be purchased with a prescription from a pharmacy. The tablet form contains 10 mg of metoclopramide hydrochloride per tablet, and the syrup form contains 5 mg of metoclopramide hydrochloride per 5 ml of syrup.
Pharmacological Classification
Adco Contromet Tablet belongs to the pharmacological class of gastrointestinal antispasmodics and cholinolytics. These are medications that act on the smooth muscles of the gastrointestinal tract and the cholinergic system, respectively.
Gastrointestinal Antispasmodics
Gastrointestinal antispasmodics are medications that reduce the spasms and contractions of the smooth muscles of the gastrointestinal tract. They are used to treat various conditions, such as irritable bowel syndrome, diverticular disease, peptic ulcer disease, and functional dyspepsia. They may also be used as an adjunct to diagnostic procedures, such as X-ray examinations, endoscopy, and colonoscopy.
Gastrointestinal antispasmodics may have different mechanisms of action, such as:
- Anticholinergic: These medications block the action of acetylcholine, a neurotransmitter that stimulates the smooth muscles of the gastrointestinal tract. Examples of anticholinergic antispasmodics are atropine, hyoscine, and propantheline.
- Calcium Channel Blocker: These medications inhibit the influx of calcium ions into the smooth muscle cells, which reduces the contractility and excitability of the smooth muscles. Examples of calcium channel blocker antispasmodics are diltiazem, nifedipine, and verapamil.
- Nitric Oxide Donor: These medications release nitric oxide, a gas that relaxes the smooth muscles of the gastrointestinal tract. Examples of nitric oxide donor antispasmodics are glyceryl trinitrate and isosorbide dinitrate.
- Opioid: These medications activate the opioid receptors in the gastrointestinal tract, which inhibit the release of acetylcholine and substance P, two neurotransmitters that stimulate the smooth muscles. Examples of opioid antispasmodics are codeine, loperamide, and diphenoxylate.
- Serotonin Antagonist: These medications block the action of serotonin, a neurotransmitter that stimulates the smooth muscles of the gastrointestinal tract. Examples of serotonin antagonist antispasmodics are alosetron, ondansetron, and granisetron.
Adco Contromet Tablet is a gastrointestinal antispasmodic that acts as a dopamine antagonist and a cholinergic stimulant. It increases the tone and amplitude of gastric contractions, relaxes the pyloric sphincter and the duodenal bulb, increases the peristaltic activity of the duodenum and jejunum, enhances the gastric emptying and intestinal transit of liquids and solids, and increases the lower esophageal sphincter pressure.
Cholinolytics
Cholinolytics are medications that inhibit the action of acetylcholine, a neurotransmitter that stimulates the cholinergic system. The cholinergic system is involved in various functions, such as:
- The contraction of the smooth muscles of the gastrointestinal tract, the urinary bladder, the bronchi, and the iris
- The secretion of saliva, gastric acid, pancreatic juice, and sweat
- The regulation of heart rate, blood pressure, and respiration
- The modulation of cognition, memory, attention, and arousal
Cholinolytics may have different mechanisms of action, such as:
- Antimuscarinic: These medications block the action of acetylcholine on the muscarinic receptors, which are located on the smooth muscles, glands, and some neurons. Examples of antimuscarinic cholinolytics are atropine, hyoscine, and ipratropium.
- Antinicotinic: These medications block the action of acetylcholine on the nicotinic receptors, which are located on the skeletal muscles, autonomic ganglia, and some neurons. Examples of antinicotinic cholinolytics are tubocurarine, hexamethonium, and mecamylamine.
Adco Contromet Tablet is a cholinolytic that acts as a cholinergic stimulant. It increases the release of acetylcholine from the myenteric plexus, and potentiates the action of neostigmine, a cholinesterase inhibitor.
Uses of Adco Contromet Tablet
Adco Contromet Tablet is used for various purposes, such as:
1. Adjunct to X-ray Examinations:
Adco Contromet Tablet is used as an adjunct to X-ray examinations of the gastrointestinal tract, such as barium meal, barium enema, and cholecystography. It helps to improve the quality of the X-ray images by:
- Increasing the tone and amplitude of gastric contractions, especially in the antrum and duodenum
- Relaxing the pyloric sphincter and the duodenal bulb
- Increasing the peristaltic activity of the duodenum and jejunum
- Enhancing the gastric emptying and intestinal transit of liquids and solids
- Increasing the lower esophageal sphincter pressure and preventing gastroesophageal reflux
These effects facilitate the passage of the contrast medium through the gastrointestinal tract, and reduce the interference of gas, food, and secretions. Adco Contromet Tablet also reduces the discomfort and pain associated with the X-ray examinations.
2. Post-Operative Hypotonia (Postvagotomy Syndrome):
Adco Contromet Tablet is used to treat post-operative hypotonia, also known as postvagotomy syndrome. This is a condition that occurs after a surgical procedure that involves cutting or removing the vagus nerve, which innervates the stomach and other organs. The vagus nerve regulates the gastric acid secretion, motility, and emptying. After the surgery, the stomach may lose its normal function and cause symptoms such as:
- Delayed gastric emptying and gastroparesis
- Dumping syndrome and diarrhea
- Bloating and abdominal pain
- Nausea and vomiting
- Malnutrition and weight loss
Adco Contromet Tablet helps to treat post-operative hypotonia by:
- Increasing the tone and amplitude of gastric contractions, especially in the antrum and duodenum
- Relaxing the pyloric sphincter and the duodenal bulb
- Increasing the peristaltic activity of the duodenum and jejunum
- Enhancing the gastric emptying and intestinal transit of liquids and solids
- Increasing the lower esophageal sphincter pressure and preventing gastroesophageal reflux
These effects improve the gastric function and reduce the symptoms of post-operative hypotonia.
3. Anti-emetic Properties:
Adco Contromet Tablet has anti-emetic properties, which means that it can prevent and treat nausea and vomiting. Nausea and vomiting are common symptoms that can be caused by various factors, such as:
- Motion sickness and vertigo
- Infections and inflammations
- Medications and chemotherapy
- Pregnancy and hormonal changes
- Psychological and emotional stress
- Food poisoning and intolerance
Adco Contromet Tablet works as an anti-emetic by:
- Stimulating the chemoreceptor trigger zone in the medulla oblongata, which is a part of the brain that controls vomiting
- Blocking the dopamine receptors in the vomiting center, which is another part of the brain that controls vomiting
- Inhibiting the central and peripheral effects of apomorphine, a dopamine agonist that induces vomiting
- Enhancing the gastric emptying and intestinal transit of liquids and solids, which reduces the stimulation of the gastric and intestinal receptors that trigger vomiting
Adco Contromet Tablet can be used to prevent and treat nausea and vomiting caused by:
i) Prevention and Treatment of Irradiation Sickness:
Irradiation sickness is a condition that occurs after exposure to high doses of radiation, such as from nuclear accidents, weapons, or medical treatments. It affects various organs and systems, such as the bone marrow, the gastrointestinal tract, the skin, and the nervous system. One of the symptoms of irradiation sickness is nausea and vomiting, which can be severe and persistent.
Adco Contromet Tablet can be used to prevent and treat nausea and vomiting caused by irradiation sickness by:
- Stimulating the chemoreceptor trigger zone in the medulla oblongata, which is sensitive to radiation
- Blocking the dopamine receptors in the vomiting center, which are activated by radiation
- Inhibiting the central and peripheral effects of apomorphine, which is used as a diagnostic test for irradiation sickness
- Enhancing the gastric emptying and intestinal transit of liquids and solids, which reduces the irritation of the gastrointestinal tract by radiation
Adco Contromet Tablet can be taken before or after the exposure to radiation, depending on the doctor’s advice.
ii) Post-Operative Vomiting:
Post-operative vomiting is a common complication that occurs after surgery, especially in the abdominal, pelvic, or thoracic regions. It can be caused by various factors, such as:
- The type, duration, and site of surgery
- The type and dose of anesthesia and analgesia
- The patient’s age, gender, and medical history
- The patient’s psychological and emotional state
- The post-operative care and environment
Post-operative vomiting can have negative consequences, such as:
- Dehydration and electrolyte imbalance
- Aspiration and pneumonia
- Wound dehiscence and infection
- Bleeding and hematoma
- Pain and discomfort
- Delayed recovery and discharge
Adco Contromet Tablet can be used to prevent and treat post-operative vomiting by:
- Stimulating the chemoreceptor trigger zone in the medulla oblongata, which is activated by anesthesia and analgesia
- Blocking the dopamine receptors in the vomiting center, which are stimulated by surgery and pain
- Inhibiting the central and peripheral effects of apomorphine, which is used as a diagnostic test for post-operative vomiting
- Enhancing the gastric emptying and intestinal transit of liquids and solids, which reduces the distension and pressure of the stomach and intestines
Adco Contromet Tablet can be taken before or after the surgery, depending on the doctor’s advice.
Contraindications
Adco Contromet Tablet has some contraindications, which means that it should not be used in certain conditions or situations. These are:
1. Gastrointestinal Conditions:
Adco Contromet Tablet should not be used in patients who have or may have:
- Mechanical obstruction, perforation, or hemorrhage of the gastrointestinal tract
- Pyloric stenosis, which is a narrowing of the opening between the stomach and the duodenum
- Gastrointestinal malignancy, which is a cancer of the digestive system
- Parkinson’s disease, which is a neurological disorder that affects the movement and coordination
- Epilepsy, which is a neurological disorder that causes seizures
- Hypersensitivity or allergy to metoclopramide hydrochloride or any of the excipients in Adco Contromet Tablet
These conditions may worsen or complicate the effects of Adco Contromet Tablet, or cause serious adverse reactions.
2. Phaeochromocytoma:
Adco Contromet Tablet should not be used in patients who have or may have phaeochromocytoma, which is a rare tumor of the adrenal glands that produces excess adrenaline and noradrenaline. These hormones regulate the blood pressure, heart rate, and metabolism.
Adco Contromet Tablet may trigger the release of these hormones, which can cause a hypertensive crisis, which is a sudden and severe increase in blood pressure that can lead to stroke, heart attack, or organ damage.
3. Convulsive Disorders:
Adco Contromet Tablet should not be used in patients who have or may have convulsive disorders, such as epilepsy, which is a neurological disorder that causes seizures. Seizures are episodes of abnormal electrical activity in the brain that affect the movement, sensation, behavior, and consciousness.
Adco Contromet Tablet may lower the seizure threshold, which means that it may make the seizures more likely or more severe. It may also interfere with the effectiveness of anticonvulsant medications, which are used to prevent or treat seizures.
Warnings and Precautions
Adco Contromet Tablet has some warnings and precautions, which means that it should be used with caution and under the supervision of a doctor in certain conditions or situations. These are:
Risk of Tardive Dyskinesia
Tardive dyskinesia is a serious and potentially irreversible condition that affects the movement and coordination. It is characterized by involuntary, repetitive, and purposeless movements of the face, tongue, lips, jaw, trunk, and limbs. It may also affect the speech, swallowing, breathing, and posture.
Tardive dyskinesia is caused by the long-term or high-dose use of dopamine antagonists, such as metoclopramide hydrochloride, which is the active ingredient in Adco Contromet Tablet. Dopamine antagonists block the action of dopamine, a neurotransmitter that regulates the movement and coordination.
The risk of tardive dyskinesia increases with the duration and dose of Adco Contromet Tablet, as well as with the age, gender, and medical history of the patient. It is more common and severe in elderly individuals, especially women, and in patients who have or had mental disorders, such as schizophrenia, bipolar disorder, or depression.
Tardive dyskinesia may not improve or may worsen after the discontinuation of Adco Contromet Tablet. There is no specific treatment for tardive dyskinesia, and the symptoms may be permanent or irreversible.
Therefore, Adco Contromet Tablet should be used for the shortest possible time and at the lowest effective dose. It should not be used for longer than 12 weeks, unless the benefits outweigh the risks. It should also be avoided or used with caution in patients who are at a higher risk of developing tardive dyskinesia, such as elderly individuals, women, and patients with mental disorders.
Discontinuation in Case of Tardive Dyskinesia
If the patient develops signs or symptoms of tardive dyskinesia, such as involuntary, repetitive, and purposeless movements of the face, tongue, lips, jaw, trunk, or limbs, Adco Contromet Tablet should be discontinued immediately and the doctor should be consulted.
The discontinuation of Adco Contromet Tablet may not improve or may worsen the symptoms of tardive dyskinesia. The doctor may prescribe other medications or therapies to manage the condition, depending on the severity and impact of the symptoms.
Special Precautions for Certain Patient Groups
Adco Contromet Tablet should be used with caution and under the supervision of a doctor in certain patient groups, such as:
a) Children
Adco Contromet Tablet is not recommended for children under the age of 1 year, as the safety and efficacy of metoclopramide hydrochloride have not been established in this age group. It may cause serious adverse effects, such as extrapyramidal symptoms, methemoglobinemia, and sulfhemoglobinemia.
Adco Contromet Tablet should be used with caution and under the supervision of a doctor in children above the age of 1 year, as they may be more sensitive to the effects of metoclopramide hydrochloride. The dosage should be adjusted according to the body weight and the indication of use. The maximum daily dose should not exceed 0.5 mg/kg or 30 mg, whichever is lower.
Adco Contromet Tablet should be avoided or used with caution in children who have or may have:
- Gastrointestinal conditions, such as mechanical obstruction, perforation, or hemorrhage of the gastrointestinal tract, pyloric stenosis, gastrointestinal malignancy, Parkinson’s disease, or epilepsy
- Phaeochromocytoma, which is a rare tumor of the adrenal glands that produces excess adrenaline and noradrenaline
- Convulsive disorders, such as epilepsy, which is a neurological disorder that causes seizures
- Hypersensitivity or allergy to metoclopramide hydrochloride or any of the excipients in Adco Contromet Tablet
b) Young Patients
Adco Contromet Tablet should be used with caution and under the supervision of a doctor in young patients, especially those below the age of 20 years, as they may be more prone to develop tardive dyskinesia, a serious and potentially irreversible condition that affects the movement and coordination.
Tardive dyskinesia is characterized by involuntary, repetitive, and purposeless movements of the face, tongue, lips, jaw, trunk, and limbs. It may also affect the speech, swallowing, breathing, and posture.
Tardive dyskinesia is caused by the long-term or high-dose use of dopamine antagonists, such as metoclopramide hydrochloride, which is the active ingredient in Adco Contromet Tablet. Dopamine antagonists block the action of dopamine, a neurotransmitter that regulates the movement and coordination.
The risk of tardive dyskinesia increases with the duration and dose of Adco Contromet Tablet, as well as with the age, gender, and medical history of the patient. It is more common and severe in elderly individuals, especially women, and in patients who have or had mental disorders, such as schizophrenia, bipolar disorder, or depression.
Tardive dyskinesia may not improve or may worsen after the discontinuation of Adco Contromet Tablet. There is no specific treatment for tardive dyskinesia, and the symptoms may be permanent or irreversible.
Therefore, Adco Contromet Tablet should be used for the shortest possible time and at the lowest effective dose in young patients. It should not be used for longer than 12 weeks, unless the benefits outweigh the risks. It should also be avoided or used with caution in young patients who are at a higher risk of developing tardive dyskinesia, such as those who have or had mental disorders.
c) Elderly Individuals
Adco Contromet Tablet should be used with caution and under the supervision of a doctor in elderly individuals, especially those above the age of 65 years, as they may be more sensitive to the effects of metoclopramide hydrochloride. They may experience more side effects, such as tardive dyskinesia, extrapyramidal symptoms, bowel upsets, drowsiness, fatigue, dizziness, restlessness, anxiety, galactorrhea, gynecomastia, transient increases in plasma aldosterone concentrations, and hypertensive crises.
The dosage of Adco Contromet Tablet should be reduced in elderly individuals, depending on the renal function, liver function, and the indication of use. The maximum daily dose should not exceed 0.25 mg/kg or 15 mg, whichever is lower.
Adco Contromet Tablet should be avoided or used with caution in elderly individuals who have or may have:
- Gastrointestinal conditions, such as mechanical obstruction, perforation, or hemorrhage of the gastrointestinal tract, pyloric stenosis, gastrointestinal malignancy, Parkinson’s disease, or epilepsy
- Phaeochromocytoma, which is a rare tumor of the adrenal glands that produces excess adrenaline and noradrenaline
- Convulsive disorders, such as epilepsy, which is a neurological disorder that causes seizures
- Hypersensitivity or allergy to metoclopramide hydrochloride or any of the excipients in Adco Contromet Tablet
Regular Review for Patients on Prolonged Therapy
Adco Contromet Tablet should be used for the shortest possible time and at the lowest effective dose, as it may cause serious and potentially irreversible side effects, such as tardive dyskinesia, extrapyramidal symptoms, bowel upsets, drowsiness, fatigue, dizziness, restlessness, anxiety, galactorrhea, gynecomastia, transient increases in plasma aldosterone concentrations, and hypertensive crises.
Adco Contromet Tablet should not be used for longer than 12 weeks, unless the benefits outweigh the risks. Patients who are on prolonged therapy with Adco Contromet Tablet should be regularly reviewed by the doctor, and the need for continued treatment should be reassessed.
The doctor may monitor the patient’s clinical condition, blood pressure, heart rate, renal function, liver function, blood count, and serum electrolytes. The doctor may also perform neurological examinations, such as the Abnormal Involuntary Movement Scale (AIMS), to detect any signs or symptoms of tardive dyskinesia or extrapyramidal symptoms.
If the patient develops any adverse effects or complications, Adco Contromet Tablet should be discontinued immediately and the doctor should be consulted.
Potential Drug Interactions
Adco Contromet Tablet may interact with other medications, which may alter the effects or increase the risk of side effects. Therefore, Adco Contromet Tablet should be used with caution and under the supervision of a doctor in patients who are taking other medications, especially:
- Anticholinergic medications, such as atropine, hyoscine, and propantheline, which may reduce the effects of Adco Contromet Tablet on the gastrointestinal tract
- Antipsychotic medications, such as haloperidol, chlorpromazine, and clozapine, which may increase the risk of tardive dyskinesia and extrapyramidal symptoms
- Antidepressant medications, such as fluoxetine, paroxetine, and sertraline, which may increase the risk of serotonin syndrome, a potentially life-threatening condition that causes agitation, confusion, tremor, muscle rigidity, fever, and seizures
- Opioid medications, such as codeine, morphine, and fentanyl, which may reduce the effects of Adco Contromet Tablet on the gastrointestinal tract and increase the risk of constipation and bowel obstruction
- Sedative medications, such as diazepam, lorazepam, and zolpidem, which may increase the risk of drowsiness, fatigue, dizziness, and impaired coordination
- Alcohol, which may increase the risk of drowsiness, fatigue, dizziness, and impaired coordination
- Digoxin, which is a medication used to treat heart failure and arrhythmias, which may have reduced absorption and effectiveness due to the increased gastric emptying and intestinal transit caused by Adco Contromet Tablet
- Cyclosporine, which is a medication used to prevent organ rejection after transplantation, which may have reduced absorption and effectiveness due to the increased gastric emptying and intestinal transit caused by Adco Contromet Tablet
- Levodopa, which is a medication used to treat Parkinson’s disease, which may have reduced effectiveness due to the antagonism of dopamine receptors by Adco Contromet Tablet
- Neostigmine, which is a medication used to treat myasthenia gravis, which may have increased effectiveness due to the potentiation of acetylcholine release by Adco Contromet Tablet
These are not all the possible drug interactions with Adco Contromet Tablet. The patient should inform the doctor about all the medications, supplements, and herbal products they are taking, before starting or stopping Adco Contromet Tablet. The doctor may adjust the dosage or frequency of Adco Contromet Tablet or the other medications, or prescribe alternative medications, depending on the interaction and the patient’s condition.
Frequently Asked Questions about Adco Contromet?
Here are some of the common questions that people may have about Adco Contromet:
Q: Is Adco Contromet safe to take during pregnancy or breastfeeding?
- A: Adco Contromet may be harmful to the unborn baby or the nursing infant. The medication may cross the placenta or pass into breast milk and cause side effects, such as abnormal movements, irritability, or withdrawal symptoms. Therefore, Adco Contromet should not be taken during pregnancy or breastfeeding, unless the potential benefits outweigh the risks. The patient should consult the doctor before taking Adco Contromet if they are pregnant, planning to become pregnant, or breastfeeding.
Q: How long does Adco Contromet take to work?
- A: Adco Contromet usually starts to work within 30 to 60 minutes after taking it orally, or within 1 to 3 minutes after taking it by injection. The effects of Adco Contromet may last for 1 to 2 hours, depending on the dose and the condition being treated.
Q: Can Adco Contromet be taken with food or on an empty stomach?
- A: Adco Contromet should be taken 30 minutes before meals and at bedtime, unless otherwise instructed by the doctor or pharmacist. This helps to prevent or reduce nausea and vomiting, and to improve the emptying of the stomach. Taking Adco Contromet with food or on a full stomach may delay or reduce its absorption and effectiveness.
Q: What should I do if I miss a dose of Adco Contromet?
- A: If the patient misses a dose of Adco Contromet, they should take it as soon as they remember.
Q: What should I do if I overdose on Adco Contromet?
- A: An overdose of Adco Contromet may cause serious side effects, such as:
- Severe drowsiness, confusion, or coma.
- Severe movement disorders, such as tremors, spasms, or rigidity.
- Severe breathing problems, such as slow or shallow breathing, or respiratory arrest.
- Severe heart problems, such as low or high blood pressure, irregular heartbeat, or cardiac arrest.
- Monitoring the vital signs, such as blood pressure, heart rate, and oxygen saturation.
- Administering intravenous fluids to maintain hydration and blood pressure.
- Using medications to counteract the effects of Adco Contromet, such as:
- Benzodiazepines, such as diazepam or lorazepam, to reduce anxiety, agitation, and seizures.
- Anticholinergics, such as atropine or glycopyrrolate, to reduce salivation, sweating, and bronchial secretions.
- Antihistamines, such as diphenhydramine or promethazine, to reduce allergic reactions and movement disorders.
- Dopamine agonists, such as bromocriptine or levodopa, to reverse the parkinsonian symptoms and tardive dyskinesia.
- Providing supportive care, such as oxygen therapy, mechanical ventilation, or cardiac resuscitation, if needed.
Q: Is Adco Contromet available over the counter?
- A: No, Adco Contromet is a prescription-only medicine that requires a doctor’s prescription to obtain. The patient should not use Adco Contromet without consulting the doctor or pharmacist, as the medication may not be suitable or safe for them.
Q: Can Adco Contromet be used in children?
- A: Adco Contromet can be used in children, but only under the supervision of a doctor. The dosage and duration of Adco Contromet for children depend on the child’s age, weight, and condition. Adco Contromet should not be used in children younger than 1 year old, as the medication may cause serious side effects, such as breathing problems, muscle spasms, or seizures. Adco Contromet should also be used with caution in children older than 1 year old, as the medication may cause movement disorders, such as tardive dyskinesia, which may be permanent even after stopping the medication. The patient should consult the doctor or pharmacist before giving Adco Contromet to their child.
Q: Can Adco Contromet cause weight gain or loss?
- A: Adco Contromet may affect the appetite and metabolism of the patient, which may result in weight changes. Some patients may experience weight gain, while others may experience weight loss. The patient should monitor their weight regularly while taking Adco Contromet, and report any significant changes to the doctor or pharmacist. The patient should also maintain a balanced diet and exercise regimen to prevent or manage weight problems.
